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Identification of immune suppressor candidates utilizing comparative transcriptional profiling in histiocytic sarcoma

Abstract Histiocytic sarcoma (HS) is a rare yet lethal malignancy with no established standard of care therapies. A lack of pre-clinical models limits our understanding of HS pathogenesis and identification of therapeutic targets. Canine HS shares multiple clinical and genetic similarities with huma...

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Auteurs principaux: Jennifer A. Lenz, Brandon Peng, Charles‑Antoine Assenmacher, Austin King, Paul J. Zhang, Robert G. Maki, M. Andres Blanco, Enrico Radaelli, Matthew J. Atherton
Format: Artigo
Langue:Inglês
Publié: Springer 2025-01-01
Collection:Cancer Immunology, Immunotherapy
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Accès en ligne:https://doi.org/10.1007/s00262-024-03908-x
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