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Efficient Peptide-Mediated In Vitro Delivery of Cas9 RNP

The toolbox for genetic engineering has quickly evolved from CRISPR/Cas9 to a myriad of different gene editors, each with promising properties and enormous clinical potential. However, a major challenge remains: delivering the CRISPR machinery to the nucleus of recipient cells in a nontoxic and effi...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Oskar Gustafsson, Julia Rädler, Samantha Roudi, Tõnis Lehto, Mattias Hällbrink, Taavi Lehto, Dhanu Gupta, Samir EL Andaloussi, Joel Z. Nordin
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2021-06-01
Schriftenreihe:Pharmaceutics
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Online-Zugang:https://www.mdpi.com/1999-4923/13/6/878
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