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The poxvirus F17 protein counteracts mitochondrially orchestrated antiviral responses

Abstract Poxviruses are unusual DNA viruses that replicate in the cytoplasm. To do so, they encode approximately 100 immunomodulatory proteins that counteract cytosolic nucleic acid sensors such as cGAMP synthase (cGAS) along with several other antiviral response pathways. Yet most of these immunomo...

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Auteurs principaux: Nathan Meade, Helen K. Toreev, Ram P. Chakrabarty, Charles R. Hesser, Chorong Park, Navdeep S. Chandel, Derek Walsh
Format: Artigo
Langue:Inglês
Publié: Nature Portfolio 2023-11-01
Collection:Nature Communications
Accès en ligne:https://doi.org/10.1038/s41467-023-43635-y
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