Research advances in the therapeutic potential of xanthine oxidoreductase inhibitors for periodontitis

Periodontitis is associated with abnormal purine metabolism, which is manifested by increased uric acid in host blood and increased expression of the purine-degrading enzyme, xanthine oxidoreductase (XOR), in periodontal tissues. Both XOR and uric acid are pro-oxidative and pro-inflammatory mediator...

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Detalhes bibliográficos

Principais autores:	LI Yongshan, WU Zhicong, WANG Zixing, YU Xihuang, LIU Xi, YU Ting
Formato:	Artigo
Idioma:	Chinês
Publicado em:	Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases 2023-12-01
coleção:	口腔疾病防治
Assuntos:	periodontitis host immune modulation purine catabolism urate-lowering drugs xanthine oxidoreductase inhibitors febuxostat allopurinol inflammation oxidative stress
Acesso em linha:	https://www.kqjbfz.com/CN/10.12016/j.issn.2096-1456.2023.12.010
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