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Thermodynamic and experimental analysis of drug nanoparticles preparation using supercritical thermal processing: Solubility of Chlorothiazide in different Co-solvents

Background/purpose: Chlorothiazide is a well-known diuretic and an antihypertensive drug with poor solubility and permeability and thus low bioavailability. Producing nanoparticles of this drug via a suitable supercritical method can enhance its therapeutic efficiency. For this purpose, supercritica...

Бүрэн тодорхойлолт

-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолч: Ahmad J. Obaidullah
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: Elsevier 2023-09-01
Цуврал:Case Studies in Thermal Engineering
Нөхцлүүд:
Онлайн хандалт:http://www.sciencedirect.com/science/article/pii/S2214157X2300518X
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