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Direct amidation of esters with nitroarenes

Direct conversion of esters to amides, while attractive, is often limited to activated esters or highly nucleophilic amines. Here the authors report a nickel-catalysed reductive coupling between unactivated esters and nitroarenes, giving a direct route to aromatic amides.

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Bibliografische Detailangaben
Hauptverfasser: Chi Wai Cheung, Marten Leendert Ploeger, Xile Hu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Portfolio 2017-03-01
Schriftenreihe:Nature Communications
Online-Zugang:https://doi.org/10.1038/ncomms14878
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