Systematic allelic analysis defines the interplay of key pathways in X chromosome inactivation
Xist RNA is the master regulator of X chromosome inactivation. Here the authors describe a systematic analysis of Xist-mediated allelic silencing in mouse ESC models and define the contribution of different pathways that regulate gene silencing.
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| Principais autores: | , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Portfolio
2019-07-01
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| Serier: | Nature Communications |
| Online adgang: | https://doi.org/10.1038/s41467-019-11171-3 |
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