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Structural mechanisms of TRPM7 activation and inhibition

Abstract The transient receptor potential channel TRPM7 is a master regulator of the organismal balance of divalent cations that plays an essential role in embryonic development, immune responses, cell mobility, proliferation, and differentiation. TRPM7 is implicated in neuronal and cardiovascular d...

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Principais autores: Kirill D. Nadezhdin, Leonor Correia, Chamali Narangoda, Dhilon S. Patel, Arthur Neuberger, Thomas Gudermann, Maria G. Kurnikova, Vladimir Chubanov, Alexander I. Sobolevsky
格式: Artigo
語言:Inglês
出版: Nature Portfolio 2023-05-01
叢編:Nature Communications
在線閱讀:https://doi.org/10.1038/s41467-023-38362-3
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