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Tracking single hiPSC-derived cardiomyocyte contractile function using CONTRAX an efficient pipeline for traction force measurement

Abstract Cardiomyocytes derived from human induced pluripotent stem cells (hiPSC-CMs) are powerful in vitro models to study the mechanisms underlying cardiomyopathies and cardiotoxicity. Quantification of the contractile function in single hiPSC-CMs at high-throughput and over time is essential to d...

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Автори: Gaspard Pardon, Alison S. Vander Roest, Orlando Chirikian, Foster Birnbaum, Henry Lewis, Erica A. Castillo, Robin Wilson, Aleksandra K. Denisin, Cheavar A. Blair, Colin Holbrook, Kassie Koleckar, Alex C. Y. Chang, Helen M. Blau, Beth L. Pruitt
Формат: Artigo
Мова:Inglês
Опубліковано: Nature Portfolio 2024-06-01
Серія:Nature Communications
Онлайн доступ:https://doi.org/10.1038/s41467-024-49755-3
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