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Constitutive activation of Nrf2 induces a stable reductive state in the mouse myocardium

Redox homeostasis regulates key cellular signaling pathways in both physiology and pathology. The cell's antioxidant response provides a defense against oxidative stress and establishes a redox tone permissive for cell signaling. The molecular regulation of the well-known Keap1/Nrf2 system acts as s...

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Principais autores: Gobinath Shanmugam, Madhusudhanan Narasimhan, Susan Tamowski, Victor Darley-Usmar, Namakkal S. Rajasekaran
格式: Artigo
语言:Inglês
出版: Elsevier 2017-08-01
丛编:Redox Biology
在线阅读:http://www.sciencedirect.com/science/article/pii/S2213231717302252
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