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Polycystin-2 mediates mechanical tension-induced osteogenic differentiation of human adipose-derived stem cells by activating transcriptional co-activator with PDZ-binding motif

Human adipose-derived stem cells (hASCs) have multi-directional differentiation potential including osteogenic differentiation. Mechanical stimulation is thought to be a key regulator of bone remodeling and has been proved to promote osteogenic differentiation of mesenchymal stem cells. However, the...

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Principais autores: Liang Wang, Yahui Lu, Guanhui Cai, Hongyu Chen, Gen Li, Luwei Liu, Lian Sun, Zhaolan Guan, Wen Sun, Chunyang Zhao, Hua Wang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-08-01
Colecção:Frontiers in Physiology
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Acesso em linha:https://www.frontiersin.org/articles/10.3389/fphys.2022.917510/full
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