Development and application of a stepwise-assembled modular biomimetic lung chip for analyzing formaldehyde-induced cellular ferroptosis

Formaldehyde poses a significant threat to human health, yet its toxicity assessment is limited by current detection methods. This study developed a modular biomimetic lung chip which consists of gas concentration gradient generator module and cell culture module, assembled using alignment holes and...

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Bibliografische Detailangaben

Hauptverfasser:	Siyu Chen, Zezhi Li, Quanping Yan, Chenfeng Hua, Pingping Shang, Kejian Liu, Junwei Zhao, Guangxiang Jin, Xiang Li, Fuwei Xie
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2025-06-01
Schriftenreihe:	Frontiers in Bioengineering and Biotechnology
Schlagworte:	microfluidic modular stepwise-assembled biomimetic lung chip formaldehyde ferroptosis
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fbioe.2025.1570270/full
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