Tumor necrosis factor mediates the impact of PM2.5 on bone mineral density: Inflammatory proteome Mendelian randomization and colocalization analyses

To assess the causal effect of particulate matter 2.5 (PM2.5) on human bone mineral density (BMD) and to explore the possible mechanism and proportion mediated by inflammation-related protein. The genetic correlation between PM2.5 and BMD was assessed using the Linkage Disequilibrium Score (LDSC), a...

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Egile Nagusiak:	Mingzheng Li, Peng Shi, Huajie Yang, Suyuan Tong, Nianfeng Qiu, Fan Yao, Yuan Du, Shuhua Xi, Fei Wang
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Elsevier 2024-01-01
Saila:	Ecotoxicology and Environmental Safety
Gaiak:	PM2.5 Bone mineral density Osteoporosis Tumor necrosis factor Mendelian randomization Drug target
Sarrera elektronikoa:	http://www.sciencedirect.com/science/article/pii/S0147651323014008
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