Bidirectional two-sample Mendelian randomization analysis investigates causal associations between cathepsins and inflammatory bowel disease

BackgroundCathepsins, key regulators of the pathology of gastrointestinal disorders such as inflammatory bowel disease (IBD), are a target protease that has attracted much attention in recent years. IBD is a chronic and relapsing inflammatory disorder of the gut. Traditional studies have shown a cor...

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Autori principali:	Na Wang, Jun Liu, Bao Chai, Jianhong Yao, Xufang Du, Qi Mei, Xuena Wang
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2024-09-01
Serie:	Frontiers in Genetics
Soggetti:	IBD cathepsins mendelian randomization genetics genome-wide association studies
Accesso online:	https://www.frontiersin.org/articles/10.3389/fgene.2024.1436407/full
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