Rapid generation and characterization of recombinant HCoV-OC43-VR1558 infectious clones expressing reporter Renilla luciferase

Viral infectious clones (ICs) serve as robust platforms for studying viral biology and screening antiviral agents using reverse genetics. However, the molecular profiles and complex limitations of human coronaviruses (HCoVs) pose a challenge to ICs development. In this study, we report a novel platf...

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Detalhes bibliográficos

Principais autores:	Fei Ye, Na Wang, Qiongge Guan, Mengwei Wang, Jiewei Sun, Desheng Zhai, Baoying Huang, Ying Zhao, Wenjie Tan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-12-01
coleção:	Biosafety and Health
Assuntos:	Infectious clones Human coronaviruses (HCoV)-OC43 Transformation-associated recombination (TAR) Reporter Renilla luciferase (Rluc)
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S259005362400137X
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