Plasmodium berghei NK65 in Combination with IFN-γ Induces Endothelial Glucocorticoid Resistance via Sustained Activation of p38 and JNK

Malaria-associated acute respiratory distress syndrome (MA-ARDS) is an often lethal complication of malaria. Currently, no adequate therapy for this syndrome exists. Although glucocorticoids (GCs) have been used to improve clinical outcome of ARDS, their therapeutic benefits remain unclear. We previ...

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Prif Awduron:	Karolina A. Zielińska, Lode de Cauwer, Sofie Knoops, Kristof Van der Molen, Alexander Sneyers, Jonathan Thommis, J. Brian De Souza, Ghislain Opdenakker, Karolien De Bosscher, Philippe E. Van den Steen
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Frontiers Media S.A. 2017-09-01
Cyfres:	Frontiers in Immunology
Pynciau:	malaria glucocorticoids endothelium MAPK interferon-γ dexamethasone
Mynediad Ar-lein:	http://journal.frontiersin.org/article/10.3389/fimmu.2017.01199/full
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