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ATP6AP1 promotes cell proliferation and tamoxifen resistance in luminal breast cancer by inducing autophagy

Abstract Autophagy is a highly conserved cellular process essential for maintaining cellular homeostasis and influencing cancer development. Lysosomal acidification and autophagosome-lysosome fusion are two important steps of autophagy degradation that are tightly regulated. Although many key protei...

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Autors principals: Zhengwei Yan, Aidi Huang, Dongwen Ma, Chenao Hong, Shengmiao Zhang, Luling He, Hai Rao, Shiwen Luo
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2025-03-01
Col·lecció:Cell Death and Disease
Accés en línia:https://doi.org/10.1038/s41419-025-07534-y
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