Meta-analysis of the global distribution of clinically relevant CYP2C8 alleles and their inferred functional consequences
Abstract Background CYP2C8 is responsible for the metabolism of 5% of clinically prescribed drugs, including antimalarials, anti-cancer and anti-inflammatory drugs. Genetic variability is an important factor that influences CYP2C8 activity and modulates the pharmacokinetics, efficacy and safety of i...
محفوظ في:
| المؤلفون الرئيسيون: | , , , , , |
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| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
BMC
2024-04-01
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| سلاسل: | Human Genomics |
| الموضوعات: | |
| الوصول للمادة أونلاين: | https://doi.org/10.1186/s40246-024-00610-y |
| الوسوم: |
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