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Levosimendan in Cardiogenic Shock: A Review of Mechanisms, Clinical Evidence, and Therapeutic Use

Levosimendan is a calcium-sensitizing inodilator that has attracted renewed attention for a potential role in the management of cardiogenic shock (CS). The pharmacological profile of levosimendan differs markedly from that of adrenergic inotropes: levosimendan augments contractile force without incr...

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Hoofdauteurs: Stefano Salvini, Valeria Trivelloni, Ilenia Monaco, Fatima Samet Bouhaik, Insaf Chouarfia, Iheb Guefrachi, Yassine Bencharef, Mounia Sedrati, Charaf Mouhand, Dario Bottigliero
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: IMR Press 2026-05-01
Reeks:Reviews in Cardiovascular Medicine
Onderwerpen:
levosimendan
cardiogenic shock
heart failure
infusions intravenous
extracorporeal membrane oxygenation
ventricular assist devices
catecholamines
phosphodiesterase inhibitors
troponin c
vasodilation
Online toegang:https://www.imrpress.com/journal/RCM/27/5/10.31083/RCM47062
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