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The phenotypes of ATG9, ATG16 and ATG9/16 knock-out mutants imply autophagy-dependent and -independent functions

Macroautophagy is a highly conserved intracellular bulk degradation system of all eukaryotic cells. It is governed by a large number of autophagy proteins (ATGs) and is crucial for many cellular processes. Here, we describe the phenotypes of Dictyostelium discoideum ATG16− and ATG9−/16− cells and co...

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Autores principales: Qiuhong Xiong, Can Ünal, Jan Matthias, Michael Steinert, Ludwig Eichinger
Formato: Artigo
Lenguaje:Inglês
Publicado: The Royal Society 2015-01-01
Colección:Open Biology
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Acceso en línea:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.150008
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