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CCL3 Enhances Antitumor Immune Priming in the Lymph Node via IFNγ with Dependency on Natural Killer Cells

Lymph node (LN) plays a critical role in tumor cell survival outside of the primary tumor sites and dictates overall clinical response in many tumor types (1, 2). Previously, we and others have demonstrated that CCL3 plays an essential role in orchestrating T cell—antigen-presenting cell (APC) encou...

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Autors principals: Frederick Allen, Peter Rauhe, David Askew, Alexander A. Tong, Joseph Nthale, Saada Eid, Jay T. Myers, Caryn Tong, Alex Y. Huang
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017-10-01
Col·lecció:Frontiers in Immunology
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Accés en línia:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01390/full
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