Inhibition of DRP-1 mitochondrial mitophagy and fission by novel α-aminophosphonates bearing pyridine: synthesis, biological evaluations, and computer-aided design

Abstract Heterocyclic compounds play a crucial role in the drug discovery process and development due to their significant presence and importance. Here, we report a comprehensive analysis of α-aminophosphonates containing pyridine (3a–g), prepared according to a clear-cut, uncomplicated procedure....

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Detalles Bibliográficos

Principais autores:	Hend A. Hekal, Maha M. Salem, Hayam A. Abd El Salam
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2024-09-01
Series:	BMC Chemistry
Assuntos:	Mitochondrial fission Dynamin-related protein 1 Antimicrobial α-Aminophosphonates Pyridine Kabachnic-fields reaction
Acceso en liña:	https://doi.org/10.1186/s13065-024-01268-2
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