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Inflammatory CSF profiles and longitudinal development of cognitive decline in sporadic and GBA-associated PD

Abstract Inflammation modifies the incidence and progression of Parkinson’s disease (PD). By using 30 inflammatory markers in CSF in 498 people with PD and 67 people with dementia with Lewy bodies (DLB) we show that: (1) levels of ICAM-1, Interleukin-8, MCP-1, MIP-1 beta, SCF and VEGF were associate...

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Detalhes bibliográficos
Principais autores: Stefanie Lerche, Milan Zimmermann, Benjamin Roeben, Isabel Wurster, Franca Laura Fries, Christian Deuschle, Katharina Waniek, Ingolf Lachmann, Meike Jakobi, Thomas O. Joos, Thomas Knorpp, Nicole Schneiderhan-Marra, Kathrin Brockmann
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Portfolio 2023-03-01
Colecção:npj Parkinson's Disease
Acesso em linha:https://doi.org/10.1038/s41531-023-00476-2
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