Enantioseparation and Determination of Penconazole in Rat Plasma by Chiral LC-MS/MS: Application to a Stereoselective Toxicokinetic Study

In this study, a specific and sensitive method of liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) was developed for the determination of penconazole enantiomers in rat plasma. The enantioseparation was achieved on a Chiralpak IC column by using acetonitrile/water (80:20, <i>v<...

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Autori principali:	Siman Ma, Jia Lun, Yanru Liu, Zhen Jiang, Xingjie Guo
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2020-06-01
Serie:	Molecules
Soggetti:	penconazole enantiomers liquid chromatography-tandem mass spectrometry enantioselective toxicokinetics
Accesso online:	https://www.mdpi.com/1420-3049/25/13/2964
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