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Invasive aspergillosis related to ibrutinib therapy for chronic lymphocytic leukemia

We report a case of invasive pulmonary aspergillosis in a patient taking ibrutinib, a Bruton's tyrosine kinase inhibitor used to treat refractory chronic lymphocytic leukemia. We hypothesize that ibrutinib promoted this infection by suppressing innate immune responses against Aspergillus. Clinicians...

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Principais autores: Benjamin Arthurs, MD, Kathy Wunderle, MD, Maylee Hsu, MD, Suil Kim, MD, PhD
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017-01-01
coleção:Respiratory Medicine Case Reports
Assuntos:
Aspergillus
Invasive aspergillosis
Ibrutinib
Bruton's tyrosine kinase
Chronic lymphocytic leukemia
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2213007117300023
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