White matter microstructure abnormalities in thalassemia patients using TBSS analysis based on DTI

Abstract Thalassemia is a hereditary hemoglobinopathy characterized by severe anemia and iron overload, which may affect brain microstructure. This study aims to investigate changes in the white matter (WM) microstructure of patients with β-thalassemia using diffusion tensor imaging (DTI) and tract-...

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Principais autores:	Mingrui Yang, Guowei Chen, Chaotian Luo, Cheng Tang, Fei Peng, Rong Kong, Peng Peng
Formato:	Artigo
Idioma:	Inglês
Publicado:	Nature Portfolio 2025-05-01
Series:	Scientific Reports
Assuntos:	Thalassemia White matter Diffusion tensor imaging Tract-based spatial statistics Microstructural abnormalities Iron overload
Acceso en liña:	https://doi.org/10.1038/s41598-025-99505-8
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