Crosslinked chitosan microparticles as a safe and efficient DNA carrier for intranasal vaccination against cutaneous leishmaniasis

Intranasal (i.n.) vaccination with adjuvant-free plasmid DNA encoding the leishmanial antigen LACK (LACK DNA) has shown to induce protective immunity against both cutaneous and visceral leishmaniasis in rodents. In the present work, we sought to evaluate the safety and effectiveness of d,l-glycerald...

Descripción completa

Detalles Bibliográficos

Autores principales:	Beatriz L.S. Costa Souza, Eduardo F. Pinto, Izabella P.S. Bezerra, Daniel C.O. Gomes, Ana Maria B. Martinez, Maria Inês Ré, Herbert L. de Matos Guedes, Bartira Rossi-Bergmann
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Elsevier 2023-12-01
Colección:	Vaccine: X
Materias:	Intranasal vaccine DNA-based vaccine Vaccine delivery systems Leishmaniasis Chitosan microparticles Glyceraldehyde crosslinking
Acceso en línea:	http://www.sciencedirect.com/science/article/pii/S2590136223001444
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!