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NUP214 in Leukemia: It’s More than Transport

NUP214 is a component of the nuclear pore complex (NPC) with a key role in protein and mRNA nuclear export. Chromosomal translocations involving the <i>NUP214</i> locus are recurrent in acute leukemia and frequently fuse the C-terminal region of NUP214 with SET and DEK, two chromatin remodeling prot...

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Autori principali: Adélia Mendes, Birthe Fahrenkrog
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2019-01-01
Serie:Cells
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Accesso online:https://www.mdpi.com/2073-4409/8/1/76
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