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Metabolism Is a Key Regulator of Induced Pluripotent Stem Cell Reprogramming

Reprogramming to pluripotency involves drastic restructuring of both metabolism and the epigenome. However, induced pluripotent stem cells (iPSC) retain transcriptional memory, epigenetic memory, and metabolic memory from their somatic cells of origin and acquire aberrant characteristics distinct fr...

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Detaylı Bibliyografya
Asıl Yazarlar: James Spyrou, David K. Gardner, Alexandra J. Harvey
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Wiley 2019-01-01
Seri Bilgileri:Stem Cells International
Online Erişim:http://dx.doi.org/10.1155/2019/7360121
Etiketler: Etiketle
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