Antiosteoporosis and bone protective effect of alpinumisoflavone in steroid-induced osteoporosis rats via alteration of apoptosis, inflammatory and RANK/RANKL/OPG signaling pathway

Objective: To estimate the bone protective effect of alpinumisoflavone, a natural prenylated isoflavonoid, against glucocorticoid-induced osteoporosis in rats. Methods: Male Wistar rats received intramuscular administration of dexamethasone (4 mg/mL) at a dose level of 7 mg/kg for 5 weeks, and then...

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Bibliografische Detailangaben

Hauptverfasser:	Jie Lian, Jun-Long Qu, Guo-Wei Zhao, Xu-Biao Ji
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Wolters Kluwer Medknow Publications 2024-10-01
Schriftenreihe:	Asian Pacific Journal of Tropical Biomedicine
Schlagworte:	osteoporosis alpinumisoflavone bone parameters inflammation oxidative stress
Online-Zugang:	https://journals.lww.com/10.4103/apjtb.apjtb_278_24
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