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MicroRNA-223 Regulates Retinal Function and Inflammation in the Healthy and Degenerating Retina

IntroductionMicroRNAs (miRNAs) are small, non-coding RNA molecules that have powerful regulatory properties, with the ability to regulate multiple messenger RNAs (mRNAs) and biological pathways. MicroRNA-223-3p (miR-223) is known to be a critical regulator of the innate immune response, and its dysr...

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Principais autores: Nilisha Fernando, Josephine H. C. Wong, Shannon Das, Catherine Dietrich, Riemke Aggio-Bruce, Adrian V. Cioanca, Yvette Wooff, Joshua A. Chu-Tan, Ulrike Schumann, Chinh Ngo, Rohan W. Essex, Camilla Dorian, Sarah A. Robertson, Si Ming Man, Jan Provis, Riccardo Natoli
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020-06-01
coleção:Frontiers in Cell and Developmental Biology
Assuntos:
microRNA-223
retinal degeneration
macrophage
neuroinflammation
retinal function
photoreceptor cell death
Acesso em linha:https://www.frontiersin.org/article/10.3389/fcell.2020.00516/full
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