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Roxadustat prevents Ang II hypertension by targeting angiotensin receptors and eNOS

The prevalence of hypertension is increasing globally, while strategies for prevention and treatment of hypertension remain limited. FG-4592 (Roxadustat) is a potentially novel, orally active small-molecule hypoxia-inducible factor (HIF) stabilizer and is being used clinically to treat chronic kidne...

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Autori principali: Jing Yu, Shuqin Wang, Wei Shi, Wei Zhou, Yujia Niu, Songming Huang, Yue Zhang, Aihua Zhang, Zhanjun Jia
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical investigation 2021-09-01
Serie:JCI Insight
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Accesso online:https://doi.org/10.1172/jci.insight.133690
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