<a name="home"></a>The P48T germline mutation and polymorphism in the CDKN2A gene of patients with melanoma
CDKN2A has been implicated as a melanoma susceptibility gene in some kindreds with a family history of this disease. Mutations in CDKN2A may produce an imbalance between functional p16ink4a and cyclin D causing abnormal cell growth. We searched for germline mutations in this gene in 22 patients with...
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| Principais autores: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Associação Brasileira de Divulgação Científica
2006-02-01
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| coleção: | Brazilian Journal of Medical and Biological Research |
| Assuntos: | |
| Acesso em linha: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000200010&tlng=en |
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