Asymmetric silane reduction of ketones and β-Keto esters catalyzed by a chiral azolium/iridium system in the presence of a base in methanol at room temperature

Asymmetric silane reduction of ketones catalyzed by a system comprising a chiral azolium salt 1 and [Ir(cod)2]BF4 (2) in the presence of a base in methanol was achieved at room temperature within 2 h. Implementing a “pre-mixing” experimental procedure improved the efficiency of the catalytic reactio...

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Autori principali:	Toshiya Matsuki, Hiro Teramoto, Ryo Ichihara, Kazuo Inui, Satoshi Sakaguchi
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2022-01-01
Serie:	Results in Chemistry
Soggetti:	Asymmetric catalysis Enantioselective reduction Hydrosilylation reaction N-Heterocyclic carbine Iridium
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2211715622000832
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