m6A reader Ythdf proteins control retrotransposon B2 repeat expression and safeguard early embryo development

Abstract N 6-methyladenosine (m6A) and its binding proteins are critical regulators of gene expression and development in mammals. Despite its extent and importance, the regulatory mechanisms of m6A-binding reader proteins Ythdf1, Ythdf2, and Ythdf3 during the early stages of mammalian development r...

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Bibliografische Detailangaben

Hauptverfasser:	Ruibao Su, Di Gao, Zongchang Du, Tie-Gang Meng, Chao Li, Lei-Ning Chen, Xiaoting Lin, Changchang Cao, Li-Hua Fan, Yanbin Dong, Sheng Li, Shi-Ming Luo, Shuai Jiang, Zhong Guo, Yulu Tian, Qing-Yuan Sun, Xiang-Hong Ou
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Springer Nature 2026-03-01
Schriftenreihe:	The EMBO Journal
Schlagworte:	Ythdf1/2/3 Proteins RNA Decay SINE/B2 Retrotransposons RNA Polymerase Ⅱ Transcription Early Embryo
Online-Zugang:	https://doi.org/10.1038/s44318-026-00728-w
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