Unsuppressed HIV infection impairs T cell responses to SARS-CoV-2 infection and abrogates T cell cross-recognition

In some instances, unsuppressed HIV has been associated with severe COVID-19 disease, but the mechanisms underpinning this susceptibility are still unclear. Here, we assessed the impact of HIV infection on the quality and epitope specificity of SARS-CoV-2 T cell responses in the first wave and secon...

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Detalhes bibliográficos

Principais autores:	Thandeka Nkosi, Caroline Chasara, Andrea O Papadopoulos, Tiza L Nguni, Farina Karim, Mahomed-Yunus S Moosa, Inbal Gazy, Kondwani Jambo, COMMIT-KZN-Team, Willem Hanekom, Alex Sigal, Zaza M Ndhlovu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	eLife Sciences Publications Ltd 2022-07-01
coleção:	eLife
Assuntos:	SARS-CoV-2 HIV T cell responses SARS-CoV-2 variants
Acesso em linha:	https://elifesciences.org/articles/78374
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