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Loss of miR-200c-3p promotes resistance to radiation therapy via the DNA repair pathway in prostate cancer

Abstract Radiotherapy represents a major curative treatment for prostate cancer (PCa), but some patients will develop radioresistance (RR) and relapse. The underlying mechanisms remain poorly understood, and miRNAs might be key players in the acquisition and maintenance of RR. Through their encapsul...

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Autori principali: Maureen Labbé, Manon Chang, Benjamin Saintpierre, Franck Letourneur, Laurence de Beaurepaire, Joëlle Véziers, Sophie Deshayes, Marine Cotinat, Jean-François Fonteneau, Christophe Blanquart, Vincent Potiron, Stéphane Supiot, Delphine Fradin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2024-10-01
Serie:Cell Death and Disease
Accesso online:https://doi.org/10.1038/s41419-024-07133-3
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