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MMP-9-responsive contact lens facilitating disease-adaptive and safer dexamethasone delivery for corneal neovascularization therapy

Corneal neovascularization (CNV), an inflammation-driven pathological process responsible for irreversible vision loss, remains an urgent unmet challenge in ophthalmic medicine. Current interventions—ranging from surgery to topical steroids—fail to prevent recurrence or avoid severe side effects lik...

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Principais autores: Chenxiao Chu, Xi Chen, Yaxin Deng, Jie Zhang, Xiaoshuang Bi, Yunfeng Ma, Mingli Wei, Jiansong Zhao, Haibing He, Jingxin Gou, Tian Yin, Xing Tang, Li Yang, Yu Zhang
Format: Artigo
Sprog:Inglês
Udgivet: KeAi Communications Co., Ltd. 2026-04-01
Serier:Asian Journal of Pharmaceutical Sciences
Fag:
Corneal neovascularization
Dexamethasone
MMP-9 responsiveness
Surface grafting
Corneal contact lens
Online adgang:http://www.sciencedirect.com/science/article/pii/S1818087626000322
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