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Model Re-Estimation: An Alternative for Poor Predictive Performance during External Evaluations? Example of Gentamicin in Critically Ill Patients

Background: An external evaluation is crucial before clinical applications; however, only a few gentamicin population pharmacokinetic (PopPK) models for critically ill patients included it in the model development. In this study, we aimed to evaluate gentamicin PopPK models developed for critically...

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Autors principals: Alexandre Duong, Chantale Simard, David Williamson, Amélie Marsot
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2022-07-01
Col·lecció:Pharmaceutics
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Accés en línia:https://www.mdpi.com/1999-4923/14/7/1426
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