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Modified Huangqi Chifeng decoction alleviates IgA nephropathy inflammation and renal fibrosis via miR-146a/TLR4/NF-κB signaling modulation

BackgroundImmunoglobulin A nephropathy (IgAN) is the most prevalent primary glomerulonephritis worldwide and a leading cause of end-stage renal disease, posing a significant threat to human health. Modified Huangqi Chifeng decoction (MHCD) has shown efficacy in ameliorating IgAN; however, its underl...

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Principais autores: Yue Shi, Jing Liu, Sijia Ma, Hangyu Duan, Xiujie Shi, Meiying Chang, Bin Yang, Mingming Zhao, Yu Zhang
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2026-07-01
Serier:Frontiers in Immunology
Fag:
IgAN
immunoglobulin A nephropathy
inflammation
miR-146a
modified Huangqi Chifeng decoction
renal fibrosis
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1867439/full
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