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Suppressor tRNAs at the interface of genetic code expansion and medicine

Suppressor transfer RNAs (sup-tRNAs) are receiving renewed attention for their promising therapeutic properties in treating genetic diseases caused by nonsense mutations. Traditionally, sup-tRNAs have been created by replacing the anticodon sequence of native tRNAs with a suppressor sequence. Howeve...

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Váldodahkkit: Aya Awawdeh, Alexander A. Radecki, Oscar Vargas-Rodriguez
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Frontiers Media S.A. 2024-05-01
Ráidu:Frontiers in Genetics
Fáttát:
Liŋkkat:https://www.frontiersin.org/articles/10.3389/fgene.2024.1420331/full
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