Conformational Dynamics Related to Membrane Fusion Observed in Single Ebola GP Molecules
The Ebola virus (EBOV) envelope glycoprotein (GP) is a membrane fusion machine required for virus entry into cells. Following the endocytosis of EBOV, the GP1 domain is cleaved by cellular cathepsins in acidic endosomes, exposing a binding site for the Niemann-Pick C1 (NPC1) receptor. The NPC1 bindi...
Gespeichert in:
| Hauptverfasser: | , , , , |
|---|---|
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
MDPI AG
2020-06-01
|
| Schriftenreihe: | Proceedings |
| Schlagworte: | |
| Online-Zugang: | https://www.mdpi.com/2504-3900/50/1/56 |
| Tags: |
Keine Tags, Fügen Sie das erste Tag hinzu!
|