Phenotypic and Molecular Biological Analysis of Polymycovirus AfuPmV-1M From Aspergillus fumigatus: Reduced Fungal Virulence in a Mouse Infection Model

The filamentous fungal pathogen Aspergillus fumigatus is one of the most common causal agents of invasive fungal infection in humans; the infection is associated with an alarmingly high mortality rate. In this study, we investigated whether a mycovirus, named AfuPmV-1M, can reduce the virulence of A...

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Principais autores:	Azusa Takahashi-Nakaguchi, Erika Shishido, Misa Yahara, Syun-ichi Urayama, Akihiro Ninomiya, Yuto Chiba, Kanae Sakai, Daisuke Hagiwara, Hiroji Chibana, Hiromitsu Moriyama, Tohru Gonoi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2020-12-01
Colecção:	Frontiers in Microbiology
Assuntos:	Aspergillus fumigatus dsRNA mycovirus hypovirulence mouse
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fmicb.2020.607795/full
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