Exosomal miR-146a-5p derived from human umbilical cord mesenchymal stem cells can alleviate antiphospholipid antibody-induced trophoblast injury and placental dysfunction by regulating the TRAF6/NF-κB axis

Abstract Exosomes originating from human umbilical cord mesenchymal stem cells (hucMSC-exos) have become a novel strategy for treating various diseases owing to their ability to regulate intercellular signal communication. However, the potential of hucMSC-exos to improve placental injury in obstetri...

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Hlavní autoři:	Qingfeng Lv, Yuan Wang, Wei Tian, Yuqiu Liu, Mengqi Gu, Xiaotong Jiang, Yanjun Cai, Ruiheng Huo, Yuchen Li, Lei Li, Xietong Wang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2023-11-01
Edice:	Journal of Nanobiotechnology
Témata:	Obstetric antiphospholipid syndrome Antiphospholipid antibodies Umbilical cord mesenchymal stem cells Exosomes miR-146a-5p
On-line přístup:	https://doi.org/10.1186/s12951-023-02179-5
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