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Base flipping in tn10 transposition: an active flip and capture mechanism.

The bacterial Tn5 and Tn10 transposases have a single active site that cuts both strands of DNA at their respective transposon ends. This is achieved using a hairpin intermediate that requires the DNA to change conformation during the reaction. In Tn5 these changes are controlled in part by a flippe...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Julien Bischerour, Ronald Chalmers
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science (PLoS) 2009-07-01
Cyfres:PLoS ONE
Mynediad Ar-lein:http://europepmc.org/articles/PMC2705183?pdf=render
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