Impairment of FOXM1 expression in mesenchymal cells from patients with myeloid neoplasms, de novo and therapy-related, may compromise their ability to support hematopoiesis

Abstract Bone marrow mesenchymal stem cells (BM-MSCs) exhibit multiple abnormalities in myelodysplastic syndromes (MDS) and acute myeloid leukemias (AML), including reduced proliferative and clonogenic capacity, altered morphology, impaired immunoregulatory properties and capacity to support hematop...

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Автори:	Giulia Falconi, Elisa Galossi, Emiliano Fabiani, Marco Pieraccioli, Serena Travaglini, Hajro Hajrullaj, Raffaella Cerretti, Raffaele Palmieri, Roberto Latagliata, Luca Maurillo, Maria Teresa Voso
Формат:	Artigo
Мова:	Inglês
Опубліковано:	Nature Portfolio 2022-12-01
Серія:	Scientific Reports
Онлайн доступ:	https://doi.org/10.1038/s41598-022-24644-1
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