Multi-modal efficacy of a chimeric vesiculovirus expressing the Morreton glycoprotein in sarcoma
Vesiculoviruses are attractive oncolytic virus platforms due to their rapid replication, appreciable transgene capacity, broad tropism, limited preexisting immunity, and tumor selectivity through type I interferon response defects in malignant cells. We developed a synthetic chimeric virus (VMG) exp...
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| Principais autores: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Elsevier
2023-06-01
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| Serier: | Molecular Therapy: Oncolytics |
| Fag: | |
| Online adgang: | http://www.sciencedirect.com/science/article/pii/S2372770523000177 |
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