Development and validation of a model incorporating choroid plexus morphology from brain MRI to predict anti-TNF-α therapy outcomes in Crohn’s disease

Abstract Objective Central nervous system involvement has been implicated in the pathophysiology of Crohn’s disease (CD). This study aimed to develop a predictive model integrating choroid plexus (CP) morphology derived from brain MRI with clinical and psychological factors to forecast treatment out...

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Главные авторы:	Mengting Huang, Shuo Huang, Qinyue Luo, Yuting Zheng, Hanting Li, Ping Han, Liangru Zhu, Heshui Shi
Формат:	Artigo
Язык:	Inglês
Опубликовано:	BMC 2026-03-01
Серии:	BMC Gastroenterology
Предметы:	Crohn’s disease Prognostic factor Neuroimaging Brain-gut axis Choroid plexus
Online-ссылка:	https://doi.org/10.1186/s12876-026-04720-w
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