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Fine-mapping and molecular characterisation of primary sclerosing cholangitis genetic risk loci

Abstract Genome-wide association studies of primary sclerosing cholangitis have identified 23 susceptibility loci. The majority of these loci reside in non-coding regions of the genome and are thought to exert their effect by perturbing the regulation of nearby genes. Here, we aim to identify these...

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Principais autores: Elizabeth C. Goode, Laura Fachal, Nikolaos Panousis, Loukas Moutsianas, Rebecca E. McIntyre, Benjamin Yu Hang Bai, Norihito Kawasaki, Alexandra Wittmann, Tim Raine, Simon M. Rushbrook, Carl A. Anderson
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Portfolio 2024-11-01
Colecção:Nature Communications
Acesso em linha:https://doi.org/10.1038/s41467-024-53602-w
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