DIDS modulates VDAC1 oligomerization to suppress intrinsic apoptosis and attenuates in vitro and in vivo RSV infection

ABSTRACT Human respiratory syncytial virus (RSV) is a major pathogen causing acute lower respiratory tract infections in infants, young children, and elderly people worldwide. Viruses often hijack host cell ion channels to optimize their intracellular environment, positioning ion channel blockers as...

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Váldodahkkit:	Siyu Lin, Xiaotong Chen, Meihua Luo, Xiaolu Cui, You Dai, Zhen Sun, Guikang Wang, Hong Peng, Ping Ling, Jinlin Long, Huifang Zhou, Changlei Luo, Yan-Fei Qi, Ke Zhang, Yu-Si Luo
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	American Society for Microbiology 2026-03-01
Ráidu:	Journal of Virology
Fáttát:	RSV DIDS VDAC1 oligomerization apoptosis in vitro and in vivo antivirus
Liŋkkat:	https://journals.asm.org/doi/10.1128/jvi.02200-25
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